Dropshare for Mac is able to work as a URL shortener without having to upload a file. Just drag & drop any URL, e.g. from Safari.app's URL bar, to the Dropshare icon or Dropshare Zone and it will be shortened. The shortened URL will be copied into your pasteboard.
Also check out Shortshare, another app from the developers of Dropshare, specialised on URL shortening.
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